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Did you mean sftpc and lung (492 results)?
Identification of hub genes and pathways in lung metastatic colorectal cancer.
Dai W, Guo C, Wang Y, Li Y, Xie R, Wu J, Yao B, Xie D, He L, Li Y, Huang H, Wang Y, Liu S. Dai W, et al. BMC Cancer. 2023 Apr 6;23(1):323. doi: 10.1186/s12885-023-10792-8. BMC Cancer. 2023. PMID: 37024866 Free PMC article.
RESULTS: The DEGs were enriched in surfactant metabolism, cell-cell communication and chemokine signaling pathways. The defined hub genes were included CLU, SFTPD, CCL18, SPP1, APOE, BGN and MMP3. Among them, CLU, SFTPD and CCL18 might be associated with the specifi …
RESULTS: The DEGs were enriched in surfactant metabolism, cell-cell communication and chemokine signaling pathways. The defined hub genes we …
Effects of ALOX5, IL6R and SFTPD gene polymorphisms on the risk of lung cancer: A case-control study in China.
Wei X, Wang C, Feng H, Li B, Jiang P, Yang J, Zhu D, Zhang S, Jin T, Meng Y. Wei X, et al. Int Immunopharmacol. 2020 Feb;79:106155. doi: 10.1016/j.intimp.2019.106155. Epub 2020 Jan 7. Int Immunopharmacol. 2020. PMID: 31918059

BACKGROUND: ALOX5, IL6R and SFTPD are all immune related genes that may be involved in the development of lung cancer. ...The rs4845626-GT/GG and rs4329505-TC genotypes were protective against lung cancer (p < 0.001). However, the rs745986-AG and rs2245121

…
BACKGROUND: ALOX5, IL6R and SFTPD are all immune related genes that may be involved in the development of lung cancer. ...The …
Identification of Crucial Genes and Signaling Pathways in Alectinib-Resistant Lung Adenocarcinoma Using Bioinformatic Analysis.
Li Z, Fan Y, Ma Y, Meng N, Li D, Wang D, Lian J, Hu C. Li Z, et al. Mol Biotechnol. 2023 Dec 24. doi: 10.1007/s12033-023-00973-y. Online ahead of print. Mol Biotechnol. 2023. PMID: 38142454
The networks of kinase, miRNA, and transcription-factor targets of SFTPD were explored using LinkedOmics. The drug sensitivity analysis of SFTPD was analyzed using the RNAactDrug database. ...The SFTPD expression was negatively correlated with the drug sensit …
The networks of kinase, miRNA, and transcription-factor targets of SFTPD were explored using LinkedOmics. The drug sensitivity analys …
Low expression of lysosome-related genes KCNE1, NPC2, and SFTPD promote cancer cell proliferation and tumor associated M2 macrophage polarization in lung adenocarcinoma.
Wang ZM, Ning ZL, Ma C, Liu TB, Tao B, Guo L. Wang ZM, et al. Heliyon. 2024 Mar 2;10(6):e27575. doi: 10.1016/j.heliyon.2024.e27575. eCollection 2024 Mar 30. Heliyon. 2024. PMID: 38509982 Free PMC article.
Finally, we characterized the expression of three LSAGs (KCNE1, NPC2, and SFTPD) in malignant lung epithelium and assessed their impact on tumor malignancy related phenotypes. ...Furthermore, we found that low expression of KCNE1, NPC2, and SFTPD promotes …
Finally, we characterized the expression of three LSAGs (KCNE1, NPC2, and SFTPD) in malignant lung epithelium and assessed the …
The dynamic dysregulated network identifies stage-specific markers during lung adenocarcinoma malignant progression and metastasis.
Wang L, Liu W, Liu K, Wang L, Yin X, Bo L, Xu H, Lin S, Feng K, Zhou X, Lin L, Fei M, Zhang C, Ning S, Zhao H. Wang L, et al. Mol Ther Nucleic Acids. 2022 Nov 22;30:633-647. doi: 10.1016/j.omtn.2022.11.019. eCollection 2022 Dec 13. Mol Ther Nucleic Acids. 2022. PMID: 36514354 Free PMC article.
Brain metastasis occurs in approximately 30% of patients with lung adenocarcinoma (LUAD) and is closely associated with poor prognosis, recurrence, and death. ...We identified 6 early advanced (HLA-DRB1, HLA-DQB1, SFTPB, SFTPC, PLA2G1B, and FOLR1), 8 advanced metastasis (R …
Brain metastasis occurs in approximately 30% of patients with lung adenocarcinoma (LUAD) and is closely associated with poor prognosi …
Prolonged injury and altered lung function after ozone inhalation in mice with chronic lung inflammation.
Groves AM, Gow AJ, Massa CB, Laskin JD, Laskin DL. Groves AM, et al. Am J Respir Cell Mol Biol. 2012 Dec;47(6):776-83. doi: 10.1165/rcmb.2011-0433OC. Epub 2012 Aug 9. Am J Respir Cell Mol Biol. 2012. PMID: 22878412 Free PMC article.
Bronchoalveolar lavage (BAL) fluid and tissue were collected 72 hours later. In Sftpd(-/-) mice, but not Sftpd(+/+) mice, increased BAL protein and nitrogen oxides were observed after ozone inhalation, indicating prolonged lung injury and oxidative stress. .. …
Bronchoalveolar lavage (BAL) fluid and tissue were collected 72 hours later. In Sftpd(-/-) mice, but not Sftpd(+/+) mice, incr …
Association of serum surfactant protein D and SFTPD gene variants with asthma in Danish children, adolescents, and young adults.
Hoffmann-Petersen B, Suffolk R, Petersen JJH, Petersen TH, Brasch-Andersen C, Høst A, Halken S, Sorensen GL, Agertoft L. Hoffmann-Petersen B, et al. Immun Inflamm Dis. 2022 Feb;10(2):189-200. doi: 10.1002/iid3.560. Epub 2021 Nov 15. Immun Inflamm Dis. 2022. PMID: 34780682 Free PMC article.
RESULTS: No differences were found in mean levels of sSP-D and SFTPD genotype among subjects with current asthma, no current asthma, and controls. Serum SP-D and SFTPD genotype were not associated with any clinical parameters of asthma. ...
RESULTS: No differences were found in mean levels of sSP-D and SFTPD genotype among subjects with current asthma, no current asthma, …
Establishment, characterization, and drug screening of low-passage patient individual non-small cell lung cancer in vitro models including the rare pleomorphic subentity.
Andus I, Prall F, Linnebacher M, Linnebacher CS. Andus I, et al. Front Oncol. 2023 May 9;13:1089681. doi: 10.3389/fonc.2023.1089681. eCollection 2023. Front Oncol. 2023. PMID: 37228492 Free PMC article.
MATERIALS AND METHODS: Here, we report on the establishment and characterization of three patient-derived cell lines (PDCs) of different subentities of non-small cell lung cancer (NSCLC): adeno-, squamous cell, and pleomorphic carcinoma. ...All cell lines expressed HLA I, …
MATERIALS AND METHODS: Here, we report on the establishment and characterization of three patient-derived cell lines (PDCs) of different sub …
Development and validation of an immune-related gene signature for prognosis in Lung adenocarcinoma.
Guo Z, Qi X, Li Z, Yang J, Sun Z, Li P, Chen M, Cao Y. Guo Z, et al. IET Syst Biol. 2023 Feb;17(1):27-38. doi: 10.1049/syb2.12057. Epub 2023 Feb 2. IET Syst Biol. 2023. PMID: 36728032 Free PMC article.
The most common type of lung cancer tissue is lung adenocarcinoma. The TCGA-LUAD cohort retrieved from the TCGA dataset was considered the internal training cohort, while GSE68465 and GSE13213 datasets from the GEO database were used as the external test cohort. ... …
The most common type of lung cancer tissue is lung adenocarcinoma. The TCGA-LUAD cohort retrieved from the TCGA dataset was co …
Genetic Association of Pulmonary Surfactant Protein Genes, SFTPA1, SFTPA2, SFTPB, SFTPC, and SFTPD With Cystic Fibrosis.
Lin Z, Thorenoor N, Wu R, DiAngelo SL, Ye M, Thomas NJ, Liao X, Lin TR, Warren S, Floros J. Lin Z, et al. Front Immunol. 2018 Oct 2;9:2256. doi: 10.3389/fimmu.2018.02256. eCollection 2018. Front Immunol. 2018. PMID: 30333828 Free PMC article.
Surfactant proteins (SP) are involved in surfactant function and innate immunity in the human lung. Both lung function and innate immunity are altered in CF, and altered SP levels and genetic association are observed in Cystic Fibrosis (CF). ...(d) No SNP-SNP intera …
Surfactant proteins (SP) are involved in surfactant function and innate immunity in the human lung. Both lung function and inn …
90 results